Leftover Meatloaf Sandwiches Recipe
There’s something incredibly satisfying about turning leftovers into a fresh, delicious meal, and that’s exactly why I adore this Leftover Meatloaf Sandwiches Recipe. It’s the perfect way to breathe new life into your meatloaf, transforming it into a warm, cheesy sandwich that’s both comforting and packed with flavor. Whether you’ve got a few slices of meatloaf sitting in your fridge after a family dinner or you’re just craving a hearty sandwich, this recipe is a total winner.
Personally, I love making these sandwiches on busy weeknights when I want something quick but still feel like I’m treating myself. The combo of that tangy barbecue mayo, melted cheese, and a little kick of mustard with the red onion takes every bite to another level. Trust me, once you try this Leftover Meatloaf Sandwiches Recipe, you’ll never look at your leftovers the same way again.
Ingredients You’ll Need
The beauty of the ingredients here is how they complement each other to create a rich, satisfying sandwich without any fuss. From creamy mayo to melty cheese and that all-important leftover meatloaf, each element is key to building that perfect layered bite.
- Mayonnaise: It adds creaminess and helps balance the tang of the barbecue sauce perfectly.
- Barbecue sauce: The smoky, sweet notes bring life and moisture to the sandwich.
- Olive oil: For a light sear on the meatloaf slices to add texture and warmth.
- Leftover meatloaf slices: The star ingredient! About an inch thick works best to hold everything together.
- Cheese slices: Thick processed or your favorite variety – I love cheddar or Swiss.
- Water: A little trick to help steam and melt the cheese gently.
- Sandwich bread: Go for your favorite kind; whole-grain works great for a hearty sandwich.
- Thinly sliced red onion: Adds a crisp bite and mild sharpness that cuts through the richness.
- Yellow mustard: The classic tangy kick that pulls all the flavors together.
Variations
I’m all about making recipes your own, and with this Leftover Meatloaf Sandwiches Recipe, you can mix things up based on what you love or what you have on hand. Don’t be shy to experiment with flavors!
- Cheese swap: I once tried smoked gouda instead of cheddar, and it added a lovely depth of smoky flavor that paired beautifully with the barbecue mayo.
- Spicy twist: Adding a slice of jalapeño or a drizzle of hot sauce gave the sandwich a welcome heat wave on a chilly night.
- Healthier option: Using whole-grain bread and low-fat mayo helps lighten it up without sacrificing taste.
- Veggie-packed: I enjoy adding fresh spinach or arugula for some greens and texture in the sandwich.
How to Make Leftover Meatloaf Sandwiches Recipe
Step 1: Whip Up Your Barbecue Mayo Spread
Start by mixing the mayonnaise and barbecue sauce in a small bowl until smoothly combined. This spread is what really jazzes up the sandwich and keeps every bite juicy. I like to prepare this first so it has a moment to meld flavors while I cook the meatloaf slices.
Step 2: Heat and Sear the Meatloaf
Heat olive oil in a skillet over medium-low heat. Place your leftover meatloaf slices in the skillet and let them cook for about 3 to 5 minutes on each side — you’re looking for a lightly golden crust that warmed through without drying out the meatloaf. This step adds a lovely texture and revives the meatloaf’s flavor.
Step 3: Melt the Cheese with a Quick Steam
Now, fold each cheese slice so it’s extra thick and place one over each warm meatloaf slice. Add a tablespoon of water to the pan and cover it quickly to let the cheese melt with a bit of steam. This only takes 30 seconds to a minute — keep an eye on it because melted cheese is a game-changer here.
Step 4: Toast the Bread and Spread the Sauce
Toast your bread just how you like it — I prefer it lightly golden so it holds up without being too crunchy. Then spread that barbecue mayo evenly on one side of all the slices to create a flavorful base for the sandwich.
Step 5: Build Your Sandwich
On one mayonnaise-coated slice, place a melty meatloaf slice with cheese, add thinly sliced red onions for a tangy crunch and drizzle yellow mustard to taste. Top it off with another slice of bread, mayo side down, and you’ve got yourself a hearty, satisfying sandwich ready to enjoy!
How to Serve Leftover Meatloaf Sandwiches Recipe

Garnishes
For me, a few extra red onion slices on the side never hurt—it amps up the flavor and adds a fresh crunch. Sometimes I toss in pickle slices for that tangy kick, or a sprinkle of freshly cracked pepper on top just before serving to wake up the sandwich.
Side Dishes
I love pairing this leftover meatloaf sandwich with crispy sweet potato fries or a fresh green salad to balance the richness. On lazy weekends, a bowl of tomato soup makes an ideal cozy combo — dipping the sandwich in warm soup is pure comfort food bliss.
Creative Ways to Present
For a fun twist when hosting friends, I sometimes cut the sandwich into mini sliders and serve them on a platter with toothpicks—great for grazing and sharing. Layering in some grilled veggies or chutney can really elevate the flavor and presentation too.
Make Ahead and Storage
Storing Leftovers
If you happen to have leftover sandwiches (though I doubt it!), wrap them tightly in foil or plastic wrap and store them in the fridge. I find they keep best when I reheat only the meatloaf part separately to avoid soggy bread.
Freezing
Freezing the assembled sandwich isn’t my go-to because the bread texture can suffer, but freezing leftover meatloaf slices works wonderfully. When you’re ready, thaw and follow the reheating steps below to recreate the sandwich fresh.
Reheating
I usually reheat the meatloaf slices in a skillet over low heat to keep them juicy and then add the cheese melting step as in the original recipe. Toast the bread fresh and assemble just before eating to keep everything tasting homemade and delicious.
FAQs
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Can I use fresh meatloaf instead of leftovers for this sandwich?
Absolutely! While this recipe is perfect for using up leftovers, freshly made meatloaf works great too. Just let the meatloaf cool completely, slice it to about an inch thick, and follow the same steps for searing and melting cheese. The sandwich will be just as delicious.
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What type of cheese melts best for this sandwich?
I recommend cheeses that melt smoothly like cheddar, Swiss, mozzarella, or processed cheese slices. These varieties get nice and gooey with the steaming step, creating that signature melty, comforting texture that makes this leftover meatloaf sandwich so irresistible.
- Can I make this sandwich ahead of time?
You can prep the barbecue mayo and meatloaf slices ahead, but assembling the sandwich right before eating keeps the bread from getting soggy. If you want to save time, toast and store your bread separately and combine everything just before serving.
- How do I prevent the sandwich bread from getting soggy?
To avoid soggy bread, make sure to toast your sandwich bread well and don’t over-spread wet ingredients like mayo and barbecue sauce. Also, assembling the sandwich right before eating and serving it warm helps the bread stay crisp and fresh.
Final Thoughts
This Leftover Meatloaf Sandwiches Recipe has become one of my favorite ways to reinvent dinner leftovers into something completely exciting and satisfying. There’s just something about those layers of melted cheese, tangy sauce, and that trusty meatloaf that feels like a big, warm hug on a plate. Give it a try next time you’re staring at leftover meatloaf—you might just find your new go-to comfort food hack.
PrintLeftover Meatloaf Sandwiches Recipe
This Leftover Meatloaf Sandwich recipe transforms your saved meatloaf into a delicious and hearty sandwich. Featuring a flavorful barbecue mayo spread, melted cheese, and fresh red onions, this sandwich is quick and easy to prepare, making a perfect satisfying meal any time of day.
- Prep Time: 10 minutes
- Cook Time: 10 minutes
- Total Time: 20 minutes
- Yield: 2 sandwiches 1x
- Category: Sandwich
- Method: Frying
- Cuisine: American
Ingredients
Sauce
- 2 tablespoons mayonnaise
- 1 tablespoon barbecue sauce
Meatloaf Filling
- 1 tablespoon olive oil
- 2 slices leftover meatloaf, about an inch thick each
- 2 slices cheese (thick processed cheese slices or your favorite variety)
- 1 tablespoon water
Sandwich Assembly
- 4 slices sandwich bread (your favorite variety)
- Thinly sliced red onion, to taste
- Yellow mustard, to taste
Instructions
- Prepare the barbecue mayo: In a small mixing bowl, whisk together the mayonnaise and barbecue sauce until well combined. Set aside this flavorful barbecue mayo for spreading on the bread.
- Cook the meatloaf slices: Heat olive oil in a skillet over medium-low to medium heat. Add the slices of leftover meatloaf to the skillet and cook for about 3 to 5 minutes on each side until the surface is slightly golden brown and the meatloaf is heated through.
- Melt the cheese: Fold each slice of cheese over so it becomes thick, then place one slice on top of each piece of meatloaf. Add 1 tablespoon of water to the skillet and cover with a lid. Let it steam for 30 seconds to 1 minute until the cheese is melted. Once melted, transfer the meatloaf slices to a plate and set aside.
- Toast the bread and spread sauce: Toast the sandwich bread slices to your preferred level of doneness. Spread the prepared barbecue mayo evenly on one side of all four slices of bread.
- Assemble the sandwiches: Place a slice of meatloaf with melted cheese on one piece of bread (barbecue mayo side up). Layer with thinly sliced red onions and drizzle with yellow mustard to taste. Top with another slice of bread, barbecue mayo side down, to complete the sandwich.
- Serve: Cut the sandwiches if desired and serve immediately while warm. Enjoy your hearty and tasty leftover meatloaf sandwich!
Notes
- You can use any type of cheese you prefer such as cheddar, Swiss, or mozzarella.
- If you like your sandwich extra crispy, toast the bread slices a bit longer or grill the assembled sandwich in a pan.
- Adjust the amount of mustard and red onion to your personal taste preferences.
- Leftover meatloaf should be fully cooked and stored properly before repurposing in this recipe.
- For a healthier option, opt for whole-grain bread and low-fat mayonnaise.
Keywords: leftover meatloaf, meatloaf sandwich, barbecue mayo, sandwich recipe, easy lunch, quick dinner
