Name: Classic Meatloaf with Ketchup Glaze Recipe
Prep time: 20 min
Cook time: 1 h
Total time: 1 h 20 min
Cuisine: American
Ingredients: 2 lbs ground beef, 85% or 80% lean; 1 medium onion, (about 1 cup), finely chopped; 1 tsp olive oil; 2 large eggs; 3 garlic cloves, minced; 2 Tbsp ketchup; 3 Tbsp fresh parsley, finely chopped; 3/4 cup Panko breadcrumbs, or gluten-free breadcrumbs; 1/3 cup milk; 1 tsp salt, or to taste; 1 tsp Italian seasoning; 1/2 tsp ground black pepper; 3/4 cup ketchup; 1 ½ tsp white vinegar; 2 Tbsp brown sugar; 1/2 tsp garlic powder; 1/2 tsp onion powder

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There’s just something so comforting about a Classic Meatloaf with Ketchup Glaze Recipe, don’t you think? It’s one of those dishes that feels like a warm hug on a plate—simple, satisfying, and made even better when shared with family or friends. I remember making this recipe during chilly evenings when I wanted something hearty without fussing over complicated steps.

What I really love about this recipe is that it hits all the right notes: savory meat, a tender crumb, and that glossy, tangy ketchup glaze that’s absolutely irresistible. Plus, it’s incredibly versatile—it works great for a casual weeknight dinner or when you want to impress guests with a classic American favorite. Trust me, once you try this Classic Meatloaf with Ketchup Glaze Recipe, it’ll likely become one of your go-to comfort foods.

Ingredients You’ll Need

These ingredients come together perfectly to create the rich flavors and moist texture this Classic Meatloaf with Ketchup Glaze Recipe is known for. When shopping, I always choose ground beef with about 80-85% lean to keep the meatloaf juicy but not greasy.

Ground Beef: I recommend 80-85% lean for the best balance between moisture and flavor.
Onion: Finely chopped for that subtle sweetness and texture without big chunks.
Olive Oil: Just a teaspoon to sauté the onion, boosting flavor for the mix.
Eggs: They’re the binding agents that help the meatloaf hold together.
Garlic Cloves: Minced fresh garlic gives that wonderful aromatic depth.
Ketchup: Used both inside the meatloaf and in the glaze for a consistent tangy sweetness.
Fresh Parsley: Adds a fresh, herbaceous note that brightens the whole dish.
Panko Breadcrumbs: These keep the texture light; gluten-free options work well too.
Milk: Moistens the breadcrumbs, giving a tender crumb.
Salt: Essential for bringing all the flavors to life—adjust to taste.
Italian Seasoning: Adds a subtle mix of herbs that’s a classic flavor match.
Black Pepper: Freshly ground for a bit of a kick.
White Vinegar: In the glaze, it cuts through the sweetness for balance.
Brown Sugar: Sweetens the glaze for that classic sticky finish.
Garlic Powder & Onion Powder: Boost the glaze’s savoriness with easy pantry staples.

Variations

One of the things I love about this Classic Meatloaf with Ketchup Glaze Recipe is how easy it is to tweak for your taste or dietary needs. I often experiment with adding extras or swapping ingredients based on what I have on hand or who I’m cooking for.

Turkey or Chicken Meatloaf: I switched to ground turkey once for a leaner option, just adding a bit more moisture like extra milk or a splash of olive oil.
Veggie Boost: Grated carrots or finely chopped mushrooms bulk it up with extra nutrients while keeping it moist.
Spicy Kick: Adding a teaspoon of smoked paprika or cayenne pepper completely transformed the flavor when I craved something bolder.
Gluten-Free Version: Using gluten-free breadcrumbs keeps it safe for my gluten-sensitive family members without losing texture.
Herb Variations: Sometimes, I swap Italian seasoning for fresh thyme or rosemary for a different herb profile that’s just as lovely.

How to Make Classic Meatloaf with Ketchup Glaze Recipe

Step 1: Sauté the Onions and Garlic

Start by heating olive oil in a skillet over medium heat, then gently cook the finely chopped onion until it’s soft and translucent—usually about 5 minutes. Add the minced garlic in the last minute so it doesn’t burn but releases its wonderful aroma. This step really layers in flavor—don’t skip it!

Step 2: Mix the Meatloaf Ingredients

In a large bowl, combine the ground beef with the sautéed onion and garlic, eggs, ketchup, chopped parsley, soaked Panko breadcrumbs, milk, salt, Italian seasoning, and pepper. I like to use my hands here because it helps me get an even mix without overworking the meat (which can make the meatloaf tough). Just gently mix until everything is combined.

Step 3: Shape and Add the Ketchup Glaze

Form your meat mixture into a loaf shape and place it on a lined or greased baking sheet or loaf pan. Now, for the best part—the glaze! In a small bowl, mix ketchup with white vinegar, brown sugar, garlic powder, and onion powder until smooth. Spread this glaze generously over the top of the meatloaf; it caramelizes in the oven to create that signature sticky, tangy coating.

Step 4: Bake Until Perfectly Cooked

Bake your meatloaf at 350°F (175°C) for about 60-70 minutes. Use a meat thermometer if you have one—165°F (74°C) is the safe temperature for ground beef. If you notice the glaze deepening too quickly, tent the meatloaf loosely with foil for the last 15 minutes of baking.

How to Serve Classic Meatloaf with Ketchup Glaze Recipe

Classic Meatloaf with Ketchup Glaze Recipe - Recipe Image

Garnishes

I usually sprinkle a little fresh chopped parsley on top for color and a fresh flavor contrast—that brightens the glaze beautifully. If I’m feeling fancy, some thinly sliced green onions add a nice crunch and subtle sharpness as well.

Side Dishes

Mashed potatoes are my classic pairing, creamy and smooth to balance the meatloaf’s texture. Roasted green beans or a simple mixed green salad with vinaigrette make the meal less heavy and more vibrant. Sometimes, I even serve it with buttery dinner rolls to soak up every bit of that ketchup glaze!

Creative Ways to Present

For holidays or special dinners, I’ve shaped the meatloaf into mini individual loaves or even meatloaf muffins—everyone loves personal portions, and they cook faster too! Another fun idea is drizzling extra glaze in a zigzag pattern on the serving platter for a polished look.

Make Ahead and Storage

Storing Leftovers

I store leftover meatloaf tightly wrapped in plastic wrap and then foil in the fridge—this keeps it moist and flavorful for up to 3 days. When I reheat it, I find that cutting it into slices first helps it warm evenly and quickly.

Freezing

Freezing works wonderfully for this Classic Meatloaf with Ketchup Glaze Recipe. I let it cool completely, then wrap it tightly in plastic and foil or place it in an airtight container. Frozen meatloaf lasts up to 3 months without losing flavor. When I’m ready to enjoy it, I thaw it overnight in the fridge before reheating.

Reheating

The best way to reheat leftover meatloaf is gently in the oven at 325°F (160°C), covered with foil to retain moisture. It usually takes about 15-20 minutes depending on thickness. Microwaving works too, but I prefer the oven method for texture and flavor preservation.

FAQs

Can I use ground turkey instead of beef in this Classic Meatloaf with Ketchup Glaze Recipe?

Absolutely! Ground turkey is a great lean alternative, but I’d recommend adding a bit more moisture—like extra milk or a splash of olive oil—since turkey tends to be leaner and can dry out more easily. Also, be gentle when mixing to keep the meatloaf tender.
What’s the best way to prevent the meatloaf from drying out?

Using a mix of breadcrumbs soaked in milk helps keep the meat moist, and including the eggs binds everything without making it dense. Also, using meat with a bit of fat (80-85% lean) ensures juiciness. Finally, tent the meatloaf with foil if the glaze browns too quickly in the oven.
Can I make this recipe gluten-free?

Yes! Just swap the Panko breadcrumbs for gluten-free breadcrumbs or crushed gluten-free crackers. The texture might be slightly different but still delicious and moist.
Is the ketchup glaze salty or very sweet?

The glaze strikes a nice balance of tangy and sweet. The vinegar cuts through the brown sugar’s sweetness, creating that classic ketchup tang enhanced by garlic and onion powders. It’s never overpowering but just the right complement to the meatloaf.
How long does the Classic Meatloaf with Ketchup Glaze Recipe keep after cooking?

Stored properly in the fridge, leftovers stay good for up to 3 days. Make sure to wrap it tightly to prevent drying out. For longer storage, freezing is best.

Final Thoughts

This Classic Meatloaf with Ketchup Glaze Recipe has been a favorite in my kitchen for years, mainly because it’s easy, reliable, and just downright delicious. It’s the kind of recipe I recommend whenever someone asks for a hearty, home-cooked meal that doesn’t stress you out. So go ahead, give it a try—you might just find this meatloaf becomes one of those cozy staples you turn to time and time again.